James R. Downing, M.D., is president and chief executive officer of St. Jude Children’s Research Hospital. He is leading a $12.9 billion commitment to accelerate progress in the research and treatment of pediatric cancer and other catastrophic diseases. This strategy includes expanding St. Jude clinical care and scientific programs in Memphis and around the globe; adding 2,300 jobs; providing $2.3 billion in new construction, renovation and capital needs; and opening new areas of research.