O’Shea is HHMI’s sixth president and the first woman to lead the Institute. Under her leadership, HHMI has expanded its strategic and financial commitments to open, inclusive science. She is responsible for spearheading new programs and initiatives to accelerate scientific discovery and influence academic science across key career stages. O’Shea previously served as vice president and chief scientific officer. A leader in the fields of gene regulation, signal transduction, and systems biology, O’Shea heads a lab at HHMI’s Janelia Research Campus. She has been an HHMI Investigator since 2000. Prior to joining HHMI leadership in 2013, O’Shea was the director of Harvard University’s Center for